> [!quote] Systemic Therapeutics > The **Systemic Therapeutics** program uses an ingestible capsule designed for needle-free delivery of biotherapeutics directly into the intestinal mucosa for enhanced systemic uptake. With more frequent administration, oral delivery has the potential to improve drug efficacy and safety as compared to current injection regimens. > > Source: <https://www.bioratherapeutics.com/pipeline/systemic-therapeutics> > [!quote] Systemic delivery of biotherapeutics through oral administration > > We are developing a pipeline of investigational drug/device combinations that are designed for oral delivery of biotherapeutics. Our proprietary liquid jet delivery is designed to increase systemic uptake and bioavailability of large molecules. > > While advancing our own pipeline, we have also partnered with Ionis Pharmaceuticals to evaluate the [[OBDS]] for delivery of antisense oligonucleotides, and we have agreements with two other leading pharmaceutical companies to evaluate delivery of their proprietary drugs via the platform.